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Environmental neuroscience : advancing the understanding of how chemical exposures impact brain health and disease : proceedings of a workshop
Bain, Lisa J.
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| 자료유형 | E-BOOK |
|---|---|
| 서명/저자사항 | Environmental neuroscience : advancing the understanding of how chemical exposures impact brain health and disease : proceedings of a workshop/ Lisa Bain, Sheena M. Posey Norris, and Clare Stroud, rapporteurs ; Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy, Health and Medicine Division, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies, the National Academies of Sciences, Engineering, Medicine. |
| 개인저자 | Bain, Lisa J.,rapporteur. Norris, Sheena M. Posey,rapporteur, Stroud, Clare,rapporteur, |
| 단체저자명 | National Academies of Sciences, Engineering, and Medicine (U.S.). Forum on Neuroscience and Nervous System Disorders.issuing body. |
| 발행사항 | Washington, DC: The National Academies Press, [2020]. |
| 형태사항 | 1 online resource (xiv, 71 pages): illustrations. |
| 기타형태 저록 | Print version: Bain, Lisa J. Environmental neuroscience. Washington, DC : The National Academies Press, [2020] 0309683092 |
| ISBN | 0309683122 9780309683128 |
| 서지주기 | Includes bibliographical references. |
| 요약 | Humans are potentially exposed to more than 80,000 toxic chemicals in the environment, yet their impacts on brain health and disease are not well understood. The sheer number of these chemicals has overwhelmed the ability to determine their individual toxicity, much less potential interactive effects. Early life exposures to chemicals can have permanent consequences for neurodevelopment and for neurodegeneration in later life. Toxic effects resulting from chemical exposure can interact with other risk factors such as prenatal stress, and persistence of some chemicals in the brain over time may result in cumulative toxicity. Because neurodevelopmental and neurodegenerative disorders -- such as attention-deficit hyperactivity disorder and Parkinson's disease -- cannot be fully explained by genetic risk factors alone, understanding the role of individual environmental chemical exposures is critical. On June 25, 2020, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders hosted a workshop to lay the foundation for future advances in environmental neuroscience. The workshop was designed to explore new opportunities to bridge the gap between what is known about the genetic contribution to brain disorders and what is known, and not known, about the contribution of environmental influences, as well as to discuss what is known about how genetic and environmental factors interact. This publication summarizes the presentation and discussion of the workshop. |
| 기금정보주기 | This activity was supported by contracts between the National Academy of Sciences and Alzheimer's Association; Cohen Veterans Bioscience; Department of Health and Human Services' Food and Drug Administration (5R13FD005362-05) and National Institutes of Health (NIH) (75N98019F00769 [Under Master Base HHSN263201800029I]) through National Center for Complementary and Integrative Health, National Eye Institute, National Institute of Mental Health, National Institute of Neurological Disorders and Stroke, National Institute on Aging, National Institute on Alcohol Abuse and Alcoholism, National Institute on Drug Abuse, and NIH Blueprint for Neuroscience Research; Department of Veterans Affairs (VA240-14-C-0057); Eisai Inc.; Eli Lilly and Company; Foundation for the National Institutes of Health; Gatsby Charitable Foundation; Janssen Research & Development, LLC; Lundbeck Research USA; Merck Research Laboratories; The Michael J. Fox Foundation for Parkinson's Research; National Multiple Sclerosis Society; National Science Foundation (DBI-1839674); One Mind; Sanofi; Society for Neuroscience; Takeda Pharmaceuticals International, Inc.; The University of Rhode Island; and Wellcome Trust. Any opinions, findings, conclusions, or recommendations expressed in this publication do not necessarily reflect the views of any organization or agency that provided support for the project. |
| 회의명 | Environmental Neuroscience: Advancing the Understanding of How Chemical Exposures Impact Brain Health and Disease (Workshop) : (2020 : Online) |
| 일반주제명 | Neurosciences --Congresses. Brain --Effect of chemicals on --Congresses. Neurosciences. Brain --metabolism Environmental Exposure --adverse effects Neurosciences Neurosciences --Congrès. Cerveau --Effets des produits chimiques sur --Congrès. Neurosciences. Brain --Effect of chemicals on. Neurosciences. |
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