National Academies of Sciences, Engineering, and Medicine (U.S.). Committee to Review DOD's Approach to Deriving an Occupational Exposure Limit for
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자료유형 | E-BOOK |
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서명/저자사항 | Review of DOD's approach to deriving an occupational exposure level for trichloroethylene/ Committee to Review DOD's Approach to Deriving an Occupational Exposure Limit for TCE, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies. |
단체저자명 | National Academies of Sciences, Engineering, and Medicine (U.S.). Committee to Review DOD's Approach to Deriving an Occupational Exposure Limit for TCE,author. |
발행사항 | Washington, DC: the National Academies Press, [2019]. |
형태사항 | 1 online resource (x, 65 pages). |
총서사항 | A consensus study report of the National Academies of Sciences, Engineering, Medicine |
ISBN | 9780309499279 0309499275 |
서지주기 | Includes bibliographical references. |
내용주기 | Introduction -- Approaches to developing exposure values -- Scoping and problem formulation -- Hazard identification -- Quantitative dose-response assessment and derivation of occuational exposure levels -- Conclusions -- Appendixes |
요약 | "Trichloroethylene (TCE) is a solvent that is used as a degreasing agent, a chemical intermediate in refrigerant manufacture, and a component of spot removers and adhesives. It is produced in mass quantities but creates dangerous vapors and is an environmental contaminant at many industrial and government facilities, including facilities run by the U.S. Department of Defense (DoD). It is important to determine the safe occupational exposure level (OEL) for the solvent in order to protect the health of workers who are exposed to its vapors. However, there are concerns that the current occupational standards insufficiently protect workers from these health threats. Review of DOD's Approach to Deriving an Occupational Exposure Level for Trichloroethylene makes recommendations to improve the DoD's approach to developing an OEL for TCE, strengthen transparency of the process, and improve confidence in the final OEL value. This report reviews the DoD's approach using a literature review, evidence synthesis based on weight of evidence [WOE], point-of-departure derivation, physiologically based pharmacokinetic modeling, extrapolation tools, and explores other elements of the process of deriving an OEL for TCE. It examines scientific approaches to developing exposure values and cancer risk levels, defining the scope of the problem, and improving hazard identification"--Publisher's description |
일반주제명 | Trichloroethylene --Threshold limit values. Solvents --Threshold limit values. Biological exposure indices (Industrial toxicology) Biological exposure indices (Industrial toxicology) |
언어 | 영어 |
바로가기 | URL |
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