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Assessing genomic sequencing information for health care decision making workshop summary [electronic resource]
Beachy, Sarah H
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| 자료유형 | E-BOOK |
|---|---|
| 서명/저자사항 | Assessing genomic sequencing information for health care decision making [electronic resource]: workshop summary/ Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy ; Sarah H. Beachy, Samuel G. Johnson, Adam C. Berger, and Steve Olson, rapporteurs ; Institute of Medicine of the National Academies. |
| 개인저자 | Beachy, Sarah H, Johnson, Samuel G, Olson, Steve,1956-, Berger, Adam C, |
| 단체저자명 | Institute of Medicine (U.S.). Roundtable on Translating Genomic-Based Research for Health,issuing body. |
| 발행사항 | Washington, D.C.: National Academies Press, [2014]. |
| 형태사항 | 1 online resource (xx, 105 pages): illustrations. |
| 기타형태 저록 | Print version: Assessing Genomic Sequencing Information for Health Care Decision Making (Workshop) (2014 : Washington, D.C.). Assessing genomic sequencing information for health care decision making Washington, D.C. : National Academies Press, 2014. 9780309304948 0309304946 |
| ISBN | 9780309304955 0309304954 |
| 서지주기 | Includes bibliographical references. |
| 내용주기 | Introduction -- How evidence is gathered and evaluated -- Patient care and health decisions -- The development of practice guidelines -- How insurers decide whether to pay for testing -- Addressing challenges. |
| 요약 | "Rapid advances in technology have lowered the cost of sequencing an individual's genome from the several billion dollars that it cost a decade ago to just a few thousand dollars today and have correspondingly greatly expanded the use of genomic information in medicine. Because of the lack of evidence available for assessing variants, evaluation bodies have made only a few recommendations for the use of genetic tests in health care. For example, organizations, such as the Evaluation of Genomic Applications in Practice and Prevention working group, have sought to set standards for the kinds of evaluations needed to make population-level health decisions. However, due to insufficient evidence, it has been challenging to recommend the use of a genetic test. An additional challenge to using large-scale sequencing in the clinic is that it may uncover "secondary," or "incidental," findings - genetic variants that have been associated with a disease but that are not necessarily related to the conditions that led to the decision to use genomic testing. Furthermore, as more genetic variants are associated with diseases, new information becomes available about genomic tests performed previously, which raises issues about how and whether to return this information to physicians and patients and also about who is responsible for the information. To help develop a better understanding of how genomic information is used for healthcare decision making, the Roundtable on Translating Genomic-Based Research for Health of the Institute of Medicine held a workshop in Washington, DC in February 2014. Stakeholders, including clinicians, researchers, patients, and government officials, discussed the issues related to the use of genomic information in medical practice. Assessing Genomic Sequencing Information for Health Care Decision Making is the summary of that workshop. This report compares and contrasts evidence evaluation processes for different clinical indications and discusses key challenges in the evidence evaluation process"--Publisher's description. |
| 일반주제명 | Medical genetics --Social aspects --Congresses. Genomics --Congresses. Genetic epidemiology --Congresses. Genetic Testing --Congresses. Genomics --Congresses. Individualized Medicine --Congresses. Decision Making --Congresses. Delivery of Health Care --Congresses. Genetics, Medical --Congresses. HEALTH & FITNESS / Diseases / General MEDICAL / Clinical Medicine MEDICAL / Diseases MEDICAL / Evidence-Based Medicine MEDICAL / Internal Medicine Genetic epidemiology. Genomics. Medical genetics --Social aspects. |
| 언어 | 영어 |
| 바로가기 | URL |
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